The majority of people tend to run Ghost on our fully managed PaaS called Ghost(Pro). This removes the headaches of server management, security monitoring, and software updates completely — and allows you to focus on the other aspects of your business where time is better spent. Some larger organizations such as Apple and Elon Musk's OpenAI team choose to run Ghost on their own private networks where they're able to make some deep core modifications to the software in order to suit specific use cases.
When you're building a publication you should always use social networks like Twitter, Facebook and Medium to promote your content & find new readers. But once you've got those readers: What next? Social networks give you zero control over your audience, and if they decide to change algorithms or disappear, then so does your readership.
V1 Proposal at BanklessDAO : NFTs as a membership subscription, auction house, art studio, art gallery …